Jornada 1
| 14 Feb 22 |  Twente Res. |
1 - 0 |  Emmen Res. |
... |
| 14 Feb 22 |  Heracles |
0 - 0 |  Heerenveen |
... |
| 22 Feb 22 |  Fortuna |
6 - 1 |  Almere City |
... |
| 24 Mar 22 |  MVV Res. |
0 - 9 |  NEC Res. |
... |
Jornada 2
| 28 Feb 22 | Heerenveen |
3 - 4 | Twente Res. |
... |
| 01 Mar 22 | Almere City |
1 - 6 | NEC Res. |
... |
| 07 Mar 22 | MVV Res. |
1 - 3 | Fortuna |
... |
| 22 Mar 22 | Emmen Res. |
1 - 0 | Heracles |
... |
Jornada 3
| 14 Mar 22 | Twente Res. |
2 - 1 | Heracles |
... |
| 21 Mar 22 | NEC Res. |
2 - 2 | Fortuna |
... |
| 04 Abr 22 | Heerenveen |
2 - 1 | Emmen Res. |
... |
| 11 Abr 22 | Almere City |
Apl | MVV Res. |
... |